A doctor may prescribe clindamycin in the form of a transvaginal suppository to treat bacterial vaginal infections. Alternatively, they may prescribe a clindamycin lotion for vaginal infections. Pregnant people in their second and third trimesters can use the lotion. A report of Susceptible (S ) indicatesthat the antimicrobial drug is likely to inhibit growth of the pathogen if theantimicrobial drug reaches the concentration usually achievable at the site ofinfection. A report of Intermediate (I) indicates that the result should beconsidered equivocal, and, if the microorganism is not fully susceptible toalternative, clinically feasible drugs, the test should be repeated. This categoryimplies possible clinical applicability in body sites where the drug isphysiologically concentrated or in situations where high dosage of drug can beused.
Pregnancy and breastfeeding
Note that this list is not all-inclusive and includes only common medications that may interact with clindamycin. You should refer to the prescribing information for clindamycin for a complete list of interactions. To help clear up your infection completely, keep using this medicine for the full time of treatment, even if you begin to feel better after a few days. When serious side effects occur, they tend to affect people taking oral or injectable forms of clindamycin. However, they can also arise in people using topical forms. If a person develops CDAD while taking clindamycin, the doctor will immediately stop their treatment with the antibiotic.
More on Drugs & Medications
RxList does not provide medical advice, diagnosis or treatment. However, the efficacy of clindamycin in treating clinical infections due to these microorganisms has not been established in adequate andwell-controlled clinical trials. Concentrations of clindamycin in the serum increasedlinearly with increased dose. Serum levels exceed the MIC (minimum inhibitoryconcentration) for most indicated organisms for at least six hours followingadministration of the usually recommended doses.
Other Medical Problems
Becauseanimal reproduction studies are not always predictive of the human response,this drug should be used during pregnancy only if clearly needed. The use of CLEOCIN HCl occasionally results in overgrowthof nonsusceptible organisms—particularly yeasts. Should superinfections occur,appropriate measures should be taken as indicated by the clinical situation. In case of such an anaphylactic or severehypersensitivity reaction, discontinue treatment permanently and instituteappropriate therapy. If CDAD is suspected or confirmed, ongoing antibiotic usenot directed against C. Difficile may need to be discontinued.Appropriate fluid and electrolyte management, protein supplementation,antibiotic treatment of C.
Clindamycin Pregnancy and Breastfeeding Warnings
Food does not affect the bioavailability of clindamycin. Call your doctor for medical advice about serious side effects or adverse reactions. You may also report side effects or health amphetamine addiction problems to the FDA at FDA-1088. Clindamycin is also indicated in the treatment of serious infections due to susceptible strains of streptococci, pneumococci, and staphylococci.
- It reduces the growth of bacteria by interfering with their ability to make proteins.
- You may report side effects to FDA at FDA-1088 or at /medwatch.
- CYP3A4 or 3A5 inducers may decrease plasma concentrations of clindamycin.
- Skipping doses may also increase your risk of further infection that is resistant to antibiotics.
In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Medical uses
If any of these effects last or get worse, tell your doctor or pharmacist promptly. Continue to take this medication until the full prescribed amount is finished, even if symptoms disappear after a few days. Stopping the medication too early may result in a return of the infection.
For more information on drug interactions, visit the RxList Drug Interaction Checker. Be sure to finish taking all the medicine your doctor prescribes, even if you feel better. Stopping clindamycin too soon may mean your infection isn't treated completely, and the bacteria can you smoke shrooms read this before you do can become resistant to antibiotics. Clindamycin is a medicine used to treat different types of bacterial infections. This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use.
Speak to your doctor about how drug interactions should be managed. Topical clindamycin can help treat bacterial infections in the vagina. Doctors use clindamycin to treat a variety of bacterial infections.
Peak concentrations in breast milk after IV administration of clindamycin 600 mg IV every six hours have been reported at 2.65 mg/L after 3.5 hours and 3.1 mg/L after 30 minutes. The most common adverse effects due to clindamycin toxicity are gastrointestinal 10 natural remedies for alcohol withdrawal ark behavioral health or allergic. There is no antidote for clindamycin toxicity, and the adverse effects will resolve with dose adjustment or discontinuation of the antibiotic. The recommendation is to measure serum electrolytes in patients with vomiting and diarrhea.
Doctors prescribe clindamycin lotions, gels, and solutions to treat acne. Pregnant people should not use clindamycin vaginal suppositories. Researchers have yet to confirm the safety of suppositories during pregnancy.
The 75 mg and 150 mg capsules contain FD&C yellow no.5 (tartrazine), which may cause allergic-type reactions (including bronchialasthma) in certain susceptible individuals. Although the overall incidence ofFD&C yellow no. 5 (tartrazine) sensitivity in the general population islow, it is frequently seen in patients who also have aspirin hypersensitivity. Serious respiratory tract infections; serious skin and soft tissue infections. You are encouraged to report negative side effects of prescription drugs to the FDA. The frequency of congenital abnormalities was not increased when pregnant women used clindamycin during the second and third trimesters. Clindamycin should not be used during the first trimester of pregnancy unless it is clearly needed because it has not been properly evaluated during the first trimester of pregnancy.
Before using clindamycin, tell your doctor if you have kidney disease, liver disease, an intestinal disorder such as colitis or Crohn's disease, or a history of asthma, eczema, or allergic skin reaction. Although appropriate studies on the relationship of age to the effects of clindamycin have not been performed in the geriatric population, no geriatric-specific problems have been documented to date. However, elderly patients are more likely to have colitis, which may require caution in patients receiving clindamycin. Inform your doctor of all medications you are currently taking, who can advise you on any possible drug interactions. Never begin taking, suddenly discontinue, or change the dosage of any medication without your doctor’s recommendation.
Clindamycin is used to treat serious infections caused by bacteria. In the future, doctors might wind up testing a babesiosis patient to see which specific resistances their parasites have developed, and then choosing appropriate drugs to counter them, Vannier said. Faced with such resistance, patients can suffer a relapse into severe babesiosis. Among those who relapse, as many as one-fifth die, researchers said. If you think there has been an overdose, call your poison control center or get medical care right away.
You can take this medication with food or on an empty stomach. If the medication upsets your stomach, take it with food. Take all of your medication as directed even if you think you are better. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Clindamycin may cause live bacterial vaccines (such as typhoid vaccine) to not work well. Tell your health care professional that you are using clindamycin before having any immunizations/vaccinations.
Difficile cause increased morbidity and mortality, as these infections can be refractory to antimicrobial therapy and may require colectomy. CDAD must be considered in all patients who present with diarrhea following antibiotic use. Careful medical history is necessary since CDAD has been reported to occur over two months after the administration of antibacterial agents. Clindamycin is effective against gram-positive aerobic cocci and most anaerobic bacteria. Take clindamycin for the full prescribed length of time.
If you notice other effects not listed above, contact your doctor or pharmacist. For the best effect, take this antibiotic at evenly spaced times. To help you remember, take this medication at the same time(s) every day. Clindamycin is a substrate of CYP3A4 and to a lesser extent, CYP3A5.